Instapaper can be used via a web-based interface, or through mobile apps for Android and iOS. Within a web browser, a "Read Later" bookmarklet can be used to save pages to a user's personal unread queue on Instapaper. Every article is automatically reformatted to remove excessive formatting and graphics.

Instapaper was initially distributed as a paid app. Later, the app became a free service, but with certain features exclusive to a "Pro" version of the app, and later an "Instapaper Premium" subscription, such as ad-free browsing, full-text search, and voice dictation on supported platforms.

Unlike a conventional social news website, which carries stories posted automatically by popularity, Give Me Something to Read is human-edited.

Example: https://www.instapaper.com/p/7039235